Liu E, Hamill O P, Salpeter M M
Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853.
Neurosci Lett. 1994 Jun 6;174(1):77-80. doi: 10.1016/0304-3940(94)90123-6.
Mouse acetylcholine receptors (AChRs) consisting of either the embryonic form (2 alpha, 1 beta, 1 delta and 1 gamma) or the adult form (2 alpha, 1 beta, 1 delta and 1 epsilon) were expressed in Xenopus laevis oocytes. As expected, the single channel conductance was approximately 52 pS and the exponential decay time constants were 2.2 and 8.2 ms for the gamma-AChR and respectively 65 pS and 0.6 and 2.8 ms for the epsilon-AChR. No difference was seen in the degradation rate between the gamma- and epsilon-containing AChRs, both having a half-life of about 5 days.
