Shephard J N, Underwood R, Evans T W
Unit of Critical Care, National Heart and Lung Institute, London, UK.
Nucl Med Commun. 1994 Aug;15(8):653-8. doi: 10.1097/00006231-199408000-00010.
Non-imaging nuclear probe systems have been available for bedside monitoring of left ventricular function since the early 1970s. The purpose of this study was to evaluate a recently developed system, the Cardioscint (Oakfield Instruments, Oxford, UK), both in the laboratory and clinically prior to its application in the critically ill on the intensive care unit. The probe system was stable at body temperature for prolonged periods and its count rate capability was adequate for those encountered clinically. An adequate period of data acquisition was shown to be important because random isotope decay produces a significant noise at these count rates. Left ventricular ejection fraction in patients with symmetrical ventricular contraction agree closely with the results obtained with radionuclide ventriculography (mean difference = 0.98%, S.D. = 2.8%, n = 30). However, in patients with asymmetrical ventricular contraction the agreement is poor (mean difference = -3.0%, S.D. = 6.2%, n = 10).
自20世纪70年代初以来，非成像核探针系统已可用于床边监测左心室功能。本研究的目的是在将最近开发的Cardioscint系统（英国牛津奥克菲尔德仪器公司）应用于重症监护病房的重症患者之前，在实验室和临床环境中对其进行评估。该探针系统在体温下长时间保持稳定，其计数率能力足以满足临床应用。研究表明，足够长的数据采集期很重要，因为在这些计数率下，随机同位素衰变会产生显著噪声。心室收缩对称的患者的左心室射血分数与放射性核素心室造影的结果非常接近（平均差异=0.98%，标准差=2.8%，n=30）。然而，心室收缩不对称的患者的一致性较差（平均差异=-3.0%，标准差=6.2%，n=10）。
