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4千赫纯音暴露对豚鼠内耳的影响：噪声暴露引起的耳蜗微音器电位、动作电位、电化学电位及K⁺离子浓度变化之间的关系。

Effect of 4 kHz tone exposure on the guinea pig inner ear: relation in the change of cochlear microphonics, action potential, electrochemical potential and K+ ion concentration induced by noise exposure.

作者信息

Sugisawa T, Nemoto R, Inada N, Yamamura K, Ishida A

机构信息

Department of Hygiene, Asahikawa Medical College, Hokkaido, Japan.

出版信息

ORL J Otorhinolaryngol Relat Spec. 1994 Sep-Oct;56(5):263-8. doi: 10.1159/000276670.

DOI:10.1159/000276670
PMID:7970610
Abstract

Using 110 male albino guinea pigs, and applying electrophysiological methods, we investigated the effects of 4 kHz tone at moderate sound pressure level on the inner ear at different exposure times (6, 12, 24 and 48 h). Longer than 12 h exposure to 4 kHz tone had a considerable effect on the hearing, inducing a decrease in the maximum output voltage of cochlear microphonics and an increase in the K+ concentration in the endolymph.

摘要

我们使用110只雄性白化豚鼠，应用电生理方法，研究了中等声压级下4kHz纯音在不同暴露时间（6、12、24和48小时）对内耳的影响。暴露于4kHz纯音超过12小时对听力有显著影响，导致耳蜗微音器电位的最大输出电压降低，内淋巴中钾离子浓度升高。

相似文献

1
Effect of 4 kHz tone exposure on the guinea pig inner ear: relation in the change of cochlear microphonics, action potential, electrochemical potential and K+ ion concentration induced by noise exposure.4千赫纯音暴露对豚鼠内耳的影响：噪声暴露引起的耳蜗微音器电位、动作电位、电化学电位及K⁺离子浓度变化之间的关系。
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2
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引用本文的文献

1
A comparative study on the effect of pure-tone exposure of the guinea pig cochlea.
Eur Arch Otorhinolaryngol. 1996;253(1-2):45-51. doi: 10.1007/BF00176703.
2
In situ real-time sequential potentiometric determinations of potassium concentrations from three cochlear regions in noise-exposed rats.
Eur Arch Otorhinolaryngol. 1996;253(4-5):201-4. doi: 10.1007/BF00171128.
3
The effect of 6 kHz tone exposure on inner ear function of the guinea pig: relation to changes in cochlear microphonics, action potential, endocochlear potential and chemical potentials of K(+)-ions and Na(+)-ions, using a double-barrel glass electrode.
Eur Arch Otorhinolaryngol. 1994;251(3):154-9. doi: 10.1007/BF00181827.