4千赫纯音暴露对豚鼠内耳的影响：噪声暴露引起的耳蜗微音器电位、动作电位、电化学电位及K⁺离子浓度变化之间的关系。
Effect of 4 kHz tone exposure on the guinea pig inner ear: relation in the change of cochlear microphonics, action potential, electrochemical potential and K+ ion concentration induced by noise exposure.
作者信息
Sugisawa T, Nemoto R, Inada N, Yamamura K, Ishida A
机构信息
Department of Hygiene, Asahikawa Medical College, Hokkaido, Japan.
出版信息
ORL J Otorhinolaryngol Relat Spec. 1994 Sep-Oct;56(5):263-8. doi: 10.1159/000276670.
PMID:7970610
Abstract
Using 110 male albino guinea pigs, and applying electrophysiological methods, we investigated the effects of 4 kHz tone at moderate sound pressure level on the inner ear at different exposure times (6, 12, 24 and 48 h). Longer than 12 h exposure to 4 kHz tone had a considerable effect on the hearing, inducing a decrease in the maximum output voltage of cochlear microphonics and an increase in the K+ concentration in the endolymph.
摘要
我们使用110只雄性白化豚鼠，应用电生理方法，研究了中等声压级下4kHz纯音在不同暴露时间（6、12、24和48小时）对内耳的影响。暴露于4kHz纯音超过12小时对听力有显著影响，导致耳蜗微音器电位的最大输出电压降低，内淋巴中钾离子浓度升高。
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