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低频超声对内耳的影响:一项使用豚鼠耳蜗的电生理学研究。

The effects of low-frequency ultrasound on the inner ear: an electrophysiological study using the guinea pig cochlea.

作者信息

Ishida A, Matsui T, Yamamura K

机构信息

Department of Hygiene, Asahikawa Medical College, Hokkaido, Japan.

出版信息

Eur Arch Otorhinolaryngol. 1993;250(1):22-6. doi: 10.1007/BF00176943.

DOI:10.1007/BF00176943
PMID:8466746
Abstract

By examining 218 albino guinea pigs, electrophysiological methods were used to investigate the effects of low frequency ultrasound at moderate sound pressure levels after long-term exposure to the inner ear. From 10 kHz to 28 kHz, low frequency ultrasound below 100 dB SPL induced significant changes in cochlear microphonics, elevated thresholds and decreased maximum output voltage of action potentials and decreased absolute values of negative potentials of the endocochlear potentials.

摘要

通过对218只白化豚鼠进行检查,采用电生理方法研究了长期暴露于内耳后,中等声压级的低频超声的影响。在10千赫至28千赫范围内,声压级低于100分贝声压级的低频超声引起了耳蜗微音器电位的显著变化、阈值升高、动作电位最大输出电压降低以及内淋巴电位负电位绝对值降低。

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引用本文的文献

1
The effect of 6 kHz tone exposure on inner ear function of the guinea pig: relation to changes in cochlear microphonics, action potential, endocochlear potential and chemical potentials of K(+)-ions and Na(+)-ions, using a double-barrel glass electrode.
Eur Arch Otorhinolaryngol. 1994;251(3):154-9. doi: 10.1007/BF00181827.

本文引用的文献

1
Stria vascularis as source of endocochlear potential.血管纹作为内淋巴电位的来源。
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2
Permeability to potassium of the endolymph-perilymph barrier and its possible relation to hair cell function.内淋巴-外淋巴屏障对钾的通透性及其与毛细胞功能的可能关系。
Exp Brain Res. 1980;40(4):457-63. doi: 10.1007/BF00236154.
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Relation between discharges in auditory nerve fibers and the whole-nerve response shown by forward masking: an empirical model for the AP.听神经纤维放电与正向掩蔽所显示的全神经反应之间的关系:动作电位的一个经验模型。
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Cochlear anatomy related to cochlear micromechanics. A review.与耳蜗微力学相关的耳蜗解剖学。综述。
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Generation mechanism of the negative endocochlear potential during early stage of anoxia.
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Exposure to industrial ultrasound: hazards, appraisal and control.工业超声暴露:危害、评估与控制。
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Temporary threshold shifts in chinchilla: electrophysiological correlates.绒鼠的暂时性阈移:电生理相关性
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