Clarke C E, Modarres-Sadeghi H, Twomey J A, Burt A A
Department of Neurology, Pinderfields District General Hospital, Wakefield, West Yorkshire, England.
Paraplegia. 1994 Aug;32(8):554-60. doi: 10.1038/sc.1994.87.
Cortical magnetic stimulation was performed in a consecutive series of 10 patients presenting within 15 days of traumatic spinal cord injury. In those patients with complete paraplegia or quadriplegia, motor evoked potentials at presentation were absent below the level of the lesion. Six months after the injury, potentials had returned in the biceps brachii and abductor pollicis brevis muscles in some quadriplegic cases, but remained absent from the tibialis anterior in all of this group. None of those with a complete lesion made a significant functional recovery. Of the three patients with incomplete quadriplegia, two showed a significant recovery after 6 months. Motor evoked potentials were recordable below the level of the lesion at presentation in these cases, although the latencies were prolonged. In the remaining patient who failed to improve, potentials were unrecordable throughout the study. This small pilot study suggests that cortical magnetic stimulation may be useful in refining the prognosis in patients with an incomplete spinal cord injury.
对连续10例在创伤性脊髓损伤15天内就诊的患者进行了皮质磁刺激。在那些完全性截瘫或四肢瘫患者中，损伤平面以下在就诊时运动诱发电位缺失。损伤6个月后，部分四肢瘫患者的肱二头肌和拇短展肌恢复了电位，但该组所有患者的胫前肌仍无电位。所有完全性损伤患者均未实现显著的功能恢复。在3例不完全性四肢瘫患者中，2例在6个月后显示出显著恢复。这些病例在就诊时损伤平面以下可记录到运动诱发电位，尽管潜伏期延长。在其余未改善的患者中，整个研究过程中均无法记录到电位。这项小型试点研究表明，皮质磁刺激可能有助于完善不完全性脊髓损伤患者的预后评估。
