Herrera R, Hobar P C, Ginsburg C M
Division of Plastic and Reconstructive Surgery, University of Texas Southwestern Medical Center, Dallas.
Pediatr Infect Dis J. 1994 Aug;13(8):734-7. doi: 10.1097/00006454-199408000-00011.
Purpura fulminans is an infrequent but sometimes catastrophic illness that usually complicates a viral, rickettsial or bacterial infection. This communication presents a retrospective review of 152 patients with meningococcemia hospitalized at Children's Medical Center of Dallas from January, 1983, through December, 1993. Eighteen (11.9%) of the 152 patients developed purpura fulminans. Thirteen (72%) of the 18 patients with purpura fulminans needed one or more surgeries including skin grafts, local debridement, microvascular flaps or amputations. Five patients (28%) died.
暴发性紫癜是一种罕见但有时具有灾难性的疾病,通常并发于病毒、立克次体或细菌感染。本文回顾性分析了1983年1月至1993年12月在达拉斯儿童医学中心住院的152例脑膜炎球菌血症患者。152例患者中有18例(11.9%)发生了暴发性紫癜。18例暴发性紫癜患者中有13例(72%)需要进行一次或多次手术,包括皮肤移植、局部清创、微血管皮瓣或截肢。5例患者(28%)死亡。