Dinh Tue A, Friedman Jeffrey, Higuera Stephen
Division of Plastic Surgery, Baylor College of Medicine, Scurlock Tower, 6560 Fannin, Suite 800, Houston, TX 77030, USA.
Clin Plast Surg. 2005 Jan;32(1):117-21, ix. doi: 10.1016/j.cps.2004.09.004.
Purpura fulminans associated with meningococcemia is a devastating disease in children. The tissue loss can be extensive and difficult to determine at the outset. The authors suggest a strategy to manage these wounds with the goal of preserving as much tissue and function as possible. At the present time, conservative therapy to the wounds appears to be the best course in the initial, critical phase, as long as no active local purulence is found. Debridement or amputation is performed when the nonviable tissue margins are delineated. Temporary coverage with allograft may be required; definitive coverage is accomplished when the local tissue perfusion has recovered. Future revisions are often necessary to improve these children's quality of life.
暴发性紫癜合并脑膜炎球菌血症是一种儿童重症疾病。组织损伤范围广泛,起初难以判断。作者提出一种处理此类伤口的策略,目标是尽可能保留组织和功能。目前,只要未发现局部有脓性分泌物,在初始关键阶段对伤口采取保守治疗似乎是最佳方案。当明确非存活组织边缘时,进行清创或截肢。可能需要用同种异体移植物进行临时覆盖;当局部组织灌注恢复后,进行确定性覆盖。为改善这些儿童的生活质量,往往需要进行后续修复手术。