Terao E, Takeuchi H, Iwamura A, Murakami Y, Harada J, Tada S
Department of Radiology, Jikei University, School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 1994 Sep 25;54(10):950-7.
We evaluated the ability of subtraction and dynamic MR imaging to accurately detect breast tumors. Sixty-five breast carcinomas and 24 fibroadenomas were examined by an SE pulse sequence using a 0.2 Tesla unit. Subtraction MR images were obtained every minute during dynamic study with Gd-DTPA. Almost all breast tumors were seen as very bright masses, and the margin of the mass was clearly demonstrated on subtraction MR images. Breast carcinomas and fibroadenomas showed characteristic time-intensity curves on dynamic study, Time-intensity curves of the early peak type and plateau type were seen in 97% of breast carcinomas, while the gradually increasing type was seen in 92% of fibroadenomas. The detectability of breast carcinoma was 98% by MRI, 98% by ultrasonography, and 87% by mammography. That of fibroadenoma was 95% by MRI, 91% by ultrasonography and 60% by mammography. Sensitivity and specificity for breast carcinoma were 98% and 92% for MRI and 97% and 71% for ultrasonography. For fibroadenoma, they were 96% and 98% for MRI and 89% and 92% for ultrasonography.
我们评估了减法磁共振成像(MR)和动态MR成像准确检测乳腺肿瘤的能力。使用0.2特斯拉设备通过SE脉冲序列对65例乳腺癌和24例纤维腺瘤进行了检查。在使用钆喷替酸葡甲胺(Gd-DTPA)的动态研究过程中,每分钟获取一次减法MR图像。几乎所有乳腺肿瘤均表现为非常亮的肿块,且肿块边缘在减法MR图像上清晰显示。乳腺癌和纤维腺瘤在动态研究中显示出特征性的时间-强度曲线,97%的乳腺癌表现为早期峰值型和平台型时间-强度曲线,而92%的纤维腺瘤表现为逐渐上升型。MRI对乳腺癌的检出率为98%,超声检查为98%,乳腺X线摄影为87%。纤维腺瘤的检出率分别为MRI 95%、超声检查91%、乳腺X线摄影60%。MRI对乳腺癌的敏感性和特异性分别为98%和92%,超声检查分别为97%和71%。对于纤维腺瘤,MRI的敏感性和特异性分别为96%和98%,超声检查分别为89%和92%。