Murakami Y, Aoki M, Harada J
Department of Radiology, Jikei University School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 1993 Apr 25;53(4):375-86.
The purpose of this study was to evaluate the diagnostic effectiveness of subtraction and dynamic MR imaging in patients with breast masses. In 23 breast cancers and six fibroadenomas, spin echo T1 images were obtained at 0.2 Tesla before and every minute after the intravenous injection of Gd-DTPA (0.1 or 0.2 mmol/kg). Subtraction images were obtained sequentially on the CRT monitor. All breast masses were enhanced after gadolinium and stood out as bright lesions on subtraction images. The tumor margin and its extension were more precisely evaluated on subtraction MR images than on conventional postcontrast MR images. Breast cancer showed a characteristic time-intensity curve with an early peak, in contrast to fibroadenoma, which showed a gradual increase in signal intensity. Subtraction MR imaging is a simple method for the evaluation of breast masses, and further, the time-intensity curve obtained by dynamic study is helpful in the differential diagnosis of lesions.
本研究的目的是评估减法和动态磁共振成像在乳腺肿块患者中的诊断有效性。对23例乳腺癌和6例纤维腺瘤患者,于静脉注射钆喷酸葡胺(0.1或0.2 mmol/kg)前及注射后每分钟,在0.2特斯拉场强下获取自旋回波T1图像。在阴极射线管显示器上顺序获取减法图像。所有乳腺肿块在钆增强后均有强化,并在减法图像上表现为明亮的病变。与传统的增强后磁共振图像相比,减法磁共振图像能更精确地评估肿瘤边缘及其范围。乳腺癌表现出具有早期峰值的特征性时间-强度曲线,而纤维腺瘤则表现为信号强度逐渐增加。减法磁共振成像是评估乳腺肿块的一种简单方法,此外,动态研究获得的时间-强度曲线有助于病变的鉴别诊断。