Amano Y, Tanabe Y, Miyashita T, Hayashi H, Horiuchi J, Nomura T, Kumazaki T
Department of Radiology, Nippon Medical School.
Nihon Igaku Hoshasen Gakkai Zasshi. 1994 Sep 25;54(10):958-64.
We investigated bone marrow in a control group, cases of aplastic anemia and post-irradiation patients by examining T1-weighted (T1WI), short TI inversion recovery (STIR), opposed phase T1WI (op-T1WI) and Gd-DTPA enhanced op-T1WI images obtained by 0.5T MRI. Bone marrow was classified into four types based on MR findings. Normal marrow showed low intensity on op-T1WI and STIR images without enhancement (I). Fatty marrow, which showed high intensity on T1WI and op-T1WI images was observed in aplastic anemia and post-irradiation patients (II). Hematopoietic marrow (III) showed low intensity on op-T1WI and enhanced, while active hematopoietic marrow (IV) revealed high intensity on both STIR and op-T1WI images and was enhanced following Gd-DTPA infusion. Aplastic anemia of moderate grade included types II, III and IV. Enhanced MR was needed to differentiate between types I and III since both types showed low intensity on op-T1WI images. Furthermore, type IV was considered as hyperplastic compared with type III. Enhanced MR and op-T1WI images were useful in evaluating hematopoiesis of bone marrow.
我们通过检查由0.5T磁共振成像（MRI）获得的T1加权（T1WI）、短TI反转恢复（STIR）、反相位T1WI（op-T1WI）和钆喷酸葡胺增强的op-T1WI图像，对对照组、再生障碍性贫血患者及放疗后患者的骨髓进行了研究。根据磁共振成像（MR）表现，骨髓被分为四种类型。正常骨髓在op-T1WI和STIR图像上呈低信号，无强化（I型）。再生障碍性贫血患者及放疗后患者可见脂肪骨髓，其在T1WI和op-T1WI图像上呈高信号（II型）。造血骨髓（III型）在op-T1WI上呈低信号且有强化，而活跃造血骨髓（IV型）在STIR和op-T1WI图像上均呈高信号，注入钆喷酸葡胺后有强化。中度再生障碍性贫血包括II型、III型和IV型。由于I型和III型在op-T1WI图像上均呈低信号，因此需要增强磁共振成像来区分这两种类型。此外，与III型相比，IV型被认为是增生性的。增强磁共振成像和op-T1WI图像有助于评估骨髓造血情况。
