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使用5-羟色胺再摄取抑制剂治疗对双腔心脏起搏无反应的颈动脉窦过敏所致复发性晕厥。

The use of serotonin reuptake inhibitors for the treatment of recurrent syncope due to carotid sinus hypersensitivity unresponsive to dual chamber cardiac pacing.

作者信息

Grubb B P, Samoil D, Kosinski D, Temesy-Armos P, Akpunonu B

机构信息

Medical College of Ohio, Toledo 43699.

出版信息

Pacing Clin Electrophysiol. 1994 Aug;17(8):1434-6. doi: 10.1111/j.1540-8159.1994.tb02463.x.

DOI:10.1111/j.1540-8159.1994.tb02463.x
PMID:7971404
Abstract

Carotid sinus hypersensitivity can be a cause of recurrent unexplained syncope in the older patient. Dual chamber cardiac pacing may relieve the bradycardia, but may not affect the vasodilatory component of this disorder. We report on two patients with carotid sinus hypersensitivity with a predominant vasodilatory component who experienced recurrent syncope following permanent pacemaker implantation. Both patients were treated with serotonin reuptake inhibitors and after 4-6 weeks of therapy had complete resolution of symptoms. We conclude that serotonin reuptake inhibitors may be useful in the treatment of recurrent syncope due to carotid sinus hypersensitivity resistant to dual chamber cardiac pacing.

摘要

颈动脉窦过敏可能是老年患者反复出现不明原因晕厥的一个原因。双腔心脏起搏可能会缓解心动过缓,但可能不会影响该疾病的血管舒张成分。我们报告了两名主要表现为血管舒张成分的颈动脉窦过敏患者,他们在植入永久性起搏器后仍反复出现晕厥。两名患者均接受了5-羟色胺再摄取抑制剂治疗,治疗4-6周后症状完全缓解。我们得出结论,5-羟色胺再摄取抑制剂可能有助于治疗因对双腔心脏起搏耐药的颈动脉窦过敏引起的反复晕厥。

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