• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[抗生素与可的松治疗分泌性中耳炎]

[Antibiotics and cortisone in the treatment of otitis media with effusion].

作者信息

Zocconi E

机构信息

Istituto per l'Infanzia, Trieste, Italia.

出版信息

Pediatr Med Chir. 1994 May-Jun;16(3):273-5.

PMID:7971452
Abstract

Persistent otitis media with effusion (OME) is a pathology very frequent in the first year of life and causes hearing loss which can be a negative factor in language and cognitive development and may result in disturbances in psychological adjustment. Generally OME has spontaneous resolution but if it persist for more than 3 months a medical or surgical treatment is compulsory. OME is frequently a result of recurrent otitis media and bacterial infection is considered to play a definitive causative role in the development of this pathology. A wide variety of medical treatments (antibiotics, aerosolized corticosteroids, oral antihistamine-decongestants, mucolytics) is indicative of lake of success. We have treated 60 children with OME with antibiotics (amoxicillin or cefaclor for 1 month) and oral steroids (prednisone for 7 days). All patients had a history for more than 3 months, without adenoid hypertrophy. Diagnosis of OME was established after pneumatic otoscopy, tympanometry and audiometry. Following the therapeutical association 53 patients showed a complete resolution of the effusion. At the follow-up after 2 months, 4 children had a recurrence of effusion. We consider this treatment with a short course of steroids and antibiotics and effective method before referral for tube placement.

摘要

持续性中耳积液(OME)是一种在出生后第一年非常常见的病症,会导致听力损失,而听力损失可能是语言和认知发展的负面因素,并可能导致心理调适障碍。一般来说,OME会自行消退,但如果持续超过3个月,则必须进行药物或手术治疗。OME通常是复发性中耳炎的结果,细菌感染被认为在这种病症的发展中起决定性的致病作用。各种各样的药物治疗(抗生素、雾化皮质类固醇、口服抗组胺减充血剂、黏液溶解剂)表明疗效不佳。我们用抗生素(阿莫西林或头孢克洛,疗程1个月)和口服类固醇(泼尼松,疗程7天)治疗了60例OME患儿。所有患者病程均超过3个月,无腺样体肥大。通过鼓气耳镜检查、鼓室图和听力测定确诊为OME。经过联合治疗,53例患者积液完全消退。在2个月后的随访中,4例患儿积液复发。我们认为这种短期使用类固醇和抗生素的治疗方法是在转诊进行置管治疗之前的一种有效方法。

相似文献

1
[Antibiotics and cortisone in the treatment of otitis media with effusion].[抗生素与可的松治疗分泌性中耳炎]
Pediatr Med Chir. 1994 May-Jun;16(3):273-5.
2
Clinical practice guideline: Otitis media with effusion.临床实践指南:中耳积液
Otolaryngol Head Neck Surg. 2004 May;130(5 Suppl):S95-118. doi: 10.1016/j.otohns.2004.02.002.
3
Prevalence and risk factors for persistent otitis media with effusion in primary school children in Istanbul, Turkey.土耳其伊斯坦布尔小学生持续性中耳积液的患病率及危险因素
Auris Nasus Larynx. 2010 Apr;37(2):145-9. doi: 10.1016/j.anl.2009.05.002. Epub 2009 Jun 21.
4
The effectiveness of nasal decongestants, oral decongestants and oral decongestant-antihistamines in the treatment of acute otitis media in children.鼻用减充血剂、口服减充血剂及口服减充血剂-抗组胺药治疗儿童急性中耳炎的疗效
Kulak Burun Bogaz Ihtis Derg. 2009 Nov-Dec;19(6):289-93.
5
Clinical Practice Guideline: Otitis Media with Effusion (Update).临床实践指南:分泌性中耳炎(更新版)
Otolaryngol Head Neck Surg. 2016 Feb;154(1 Suppl):S1-S41. doi: 10.1177/0194599815623467.
6
Antibiotics for otitis media with effusion in children.儿童分泌性中耳炎的抗生素治疗
Cochrane Database Syst Rev. 2012 Sep 12(9):CD009163. doi: 10.1002/14651858.CD009163.pub2.
7
Acute otitis media disease management.急性中耳炎的疾病管理。
Minerva Pediatr. 2003 Oct;55(5):415-38.
8
Efficacy of amoxicillin with and without decongestant-antihistamine for otitis media with effusion in children. Results of a double-blind, randomized trial.阿莫西林联合与不联合减充血剂-抗组胺药治疗儿童分泌性中耳炎的疗效。一项双盲随机试验的结果
N Engl J Med. 1987 Feb 19;316(8):432-7. doi: 10.1056/NEJM198702193160803.
9
The effect of ventilation tubes on language development in infants with otitis media with effusion: A randomized trial.通气管对中耳积液婴儿语言发育的影响:一项随机试验。
Pediatrics. 2000 Sep;106(3):E42.
10
Antibiotics for otitis media with effusion.
Minerva Pediatr. 2004 Oct;56(5):481-95.

引用本文的文献

1
Topical and oral steroids for otitis media with effusion (OME) in children.局部和口服类固醇治疗儿童分泌性中耳炎(OME)。
Cochrane Database Syst Rev. 2023 Dec 13;12(12):CD015255. doi: 10.1002/14651858.CD015255.pub2.
2
Antibiotics for otitis media with effusion (OME) in children.儿童分泌性中耳炎(OME)的抗生素治疗。
Cochrane Database Syst Rev. 2023 Oct 23;10(10):CD015254. doi: 10.1002/14651858.CD015254.pub2.
3
Antibiotics for otitis media with effusion in children.儿童分泌性中耳炎的抗生素治疗
Cochrane Database Syst Rev. 2016 Jun 12;2016(6):CD009163. doi: 10.1002/14651858.CD009163.pub3.