Gerstenbrand F, Harrer-Kuhnert G, Mamoli G
Wien Klin Wochenschr. 1976 Dec 10;88(23):760-2.
The therapeutic effect of n-dipropylacetate (DPA) is described in 20 patients with cerebral or spinal spasticity. Improvement was ween in 8 out of 11 patients with cerebral spasticity, 3 out of 5 patients with spinal spasticity and 3 out of 4 cases who had sustained perinatal damage. Satisfactory clinical amelioration and improvement in the EEG was observed in myoclonia, particularly of the Unverricht-Lundborg type.
本文描述了20例脑性或脊髓性痉挛患者使用二丙基乙酸酯(DPA)的治疗效果。11例脑性痉挛患者中有8例病情改善,5例脊髓性痉挛患者中有3例病情改善,4例围产期持续性损伤患者中有3例病情改善。在肌阵挛患者中,尤其是昂韦里希特-伦德伯格型肌阵挛患者,观察到临床症状得到令人满意的改善且脑电图有所改善。