对CHP100 C-myc表达进行反义抑制会导致体外生长动力学降低以及体内肿瘤发生能力丧失。 - Suppr | 超能文献

Antisense inhibition of CHP100 C-myc expression results in reduced in vitro growth kinetics and loss of in vivo tumorigenesis.

作者信息

Rosolen A, Toretsky J, Neckers L

机构信息

Department of Pediatrics, University of Padova, Italy.

出版信息

Prog Clin Biol Res. 1994;385:95-101.

Abstract

摘要

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Antisense inhibition of CHP100 C-myc expression results in reduced in vitro growth kinetics and loss of in vivo tumorigenesis.对CHP100 C-myc表达进行反义抑制会导致体外生长动力学降低以及体内肿瘤发生能力丧失。

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2

Antisense suppression of N-myc expression inhibits the transdifferentiation of neuroectoderm tumor cell lines.N-myc表达的反义抑制作用可抑制神经外胚层肿瘤细胞系的转分化。

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Antisense inhibition of N-myc reduces cell growth but does not affect c-myc expression in the neuroepithelioma cell line CHP100.N-myc的反义抑制降低了神经上皮瘤细胞系CHP100中的细胞生长，但不影响c-myc的表达。

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[Effects of antisense N-myc gene on nerve growth factor-induced differentiation of neuroblastoma cell line].[反义N-myc基因对神经生长因子诱导神经母细胞瘤细胞系分化的影响]

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Expression of memory, differentiation, and repression of c-myc and p53 genes in human RD/TE-671 cells induced by a ureido-derivative of pyridine (UDP-4).

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Association of the decreased expression of alpha3beta1 integrin with the altered cell: environmental interactions and enhanced soft agar cloning ability of c-myc-overexpressing small cell lung cancer cells.α3β1整合素表达降低与细胞环境相互作用改变及c-myc过表达的小细胞肺癌细胞软琼脂克隆能力增强的关联

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C-myc expression affects proliferation but not terminal differentiation or survival of explanted erythroid progenitor cells.C-myc的表达影响外植的红系祖细胞的增殖，但不影响其终末分化或存活。

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Reduction of c-myc expression by an antisense approach under Cre/loxP switching induces apoptosis in human liver cancer cells.在Cre/loxP开关作用下，通过反义方法降低c-myc表达可诱导人肝癌细胞凋亡。

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Decreased N-myc expression in human medulloblastoma cell lines during differentiation.人髓母细胞瘤细胞系在分化过程中N-myc表达降低。

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