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接受镭治疗皮肤血管瘤的儿童不同器官的吸收剂量估计。

Estimates of absorbed dose in different organs in children treated with radium for skin hemangiomas.

作者信息

Lundell M

机构信息

Department of Hospital Physics, Karolinska Hospital, Stockholm, Sweden.

出版信息

Radiat Res. 1994 Dec;140(3):327-33.

PMID:7972684
Abstract

Between 1930 and 1959, more than 10,000 infants were treated at Radiumhemmet, Stockholm, with radium (226Ra) needles and/or tubes for hemangioma of the skin. Absorbed dose to the brain, eye lenses, parotid glands, thyroid gland, breast anlage, lungs, stomach, intestine, ovaries, testicles and bone marrow were calculated for each individual. The mean absorbed dose to the different organs ranged from 0.06 to 0.48 Gy. The highest absorbed dose was given to the breast (maximum 47.7 Gy). There was a wide dose range for each organ which was due mainly to differences in the distance between the applicator and the organ. The absorbed dose to all organs decreased on average by 32% during the study period. This was due to a 25% decrease in the treatment time and a change in the distribution of the treatment sites.

摘要

1930年至1959年间,超过10000名婴儿在斯德哥尔摩镭疗医院接受了镭(226Ra)针剂和/或导管治疗皮肤血管瘤。计算了每个个体大脑、晶状体、腮腺、甲状腺、乳腺原基、肺、胃、肠、卵巢、睾丸和骨髓的吸收剂量。不同器官的平均吸收剂量范围为0.06至0.48戈瑞。乳腺接受的吸收剂量最高(最大47.7戈瑞)。每个器官的剂量范围很广,这主要是由于施源器与器官之间距离的差异。在研究期间,所有器官的吸收剂量平均下降了32%。这是由于治疗时间减少了25%以及治疗部位分布的变化。

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