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猪原位同种异体肝移植的麻醉

Anaesthesia for orthotopic allogenic liver transplantation in pigs.

作者信息

Czajkowski J, Deszkiewicz A, Polański J, Ruka M, Olszewski W

出版信息

Anaesth Resusc Intensive Ther. 1976 Jul-Sep;4(3):149-58.

PMID:797275
Abstract

Anaesthesia with a mixture of halothane, nitrous oxide and oxygen was used for allogenic liver transplantation in 24 pigs. All animals had haemodynamic disturbances due to the technique of the operation: metabolic acidosis, disturbances of bioelectric activity of the heart and electrolyte level changes. The methods of management of these disturbances are discussed. Favourable results were obtained when transfusing heparinized stored blood in place of initially used ACD blood which increased the intensity of metabolic acidosis. Details of the technique and method of anaesthesia and monitoring of animals during operation are discussed.

摘要

对24头猪进行同种异体肝移植时采用氟烷、氧化亚氮和氧气混合麻醉。由于手术操作技术,所有动物均出现血流动力学紊乱:代谢性酸中毒、心脏生物电活动紊乱和电解质水平变化。讨论了这些紊乱的处理方法。用肝素化库存血代替最初使用的ACD血进行输血时取得了良好效果,因为ACD血会加重代谢性酸中毒。文中讨论了手术期间动物麻醉及监测的技术和方法细节。

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