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腮腺肿瘤适形治疗的剂量控制

Dosimetric control of conformal treatment of parotid gland tumours.

作者信息

Essers M, Keus R, Lanson J H, Mijnheer B J

机构信息

The Netherlands Cancer Institute, Antoni van Leeuwenhoek Huis, Amsterdam.

出版信息

Radiother Oncol. 1994 Aug;32(2):154-62. doi: 10.1016/0167-8140(94)90102-3.

Abstract

The purpose of this study was to determine the dosimetric accuracy of the treatment of parotid gland tumours using 8 MV X-ray beams. These tumours are generally situated near the patient's skin. Entrance in vivo dose measurements with diodes were obtained for 20 patients during 5 sessions per patient, in the anterior-oblique and posterior-oblique wedged fields, on the central beam axis as well as in points situated in a cranial plane 2 or 3 cm off-axis. Phantom measurements were performed in order to determine the actual position of the 95% isodose surface. The measurements were compared with calculations performed with our three-dimensional treatment planning system. The reproducibility of the diode measurements on patients was found to be 1.4% (1 SD). The total accuracy in the entrance dose determination for the average of 2 measurements was 1.8% (1 SD). The central axis entrance dose for the anterior field was on average 1.5% +/- 3.2% (1 SD) higher than the calculated value. For the posterior field, the difference was 0.9% +/- 3.1% (1 SD). The deviations for the off-axis points were somewhat smaller, mainly due to overestimation of the block effect in the calculations. The value of the dose at the isocentre obtained by extrapolation of the measured entrance dose values, differed 0.3% +/- 2.1% from the calculations. The accuracy in dose determination at the isocentre was 2% (1 SD). After correction for the difference in prescribed and actual source-to-skin distance, the results showed good agreement with phantom measurements on a polystyrene phantom without inhomogeneities, performed both with diodes and an ionization chamber.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本研究的目的是确定使用8兆伏X射线束治疗腮腺肿瘤的剂量测定准确性。这些肿瘤通常位于患者皮肤附近。在20名患者的每个患者5个疗程中,通过二极管进行体内入射剂量测量,测量在前斜和后斜楔形野的中心束轴上以及位于离轴2或3厘米的颅平面中的点上进行。进行体模测量以确定95%等剂量面的实际位置。将测量结果与使用我们的三维治疗计划系统进行的计算进行比较。发现二极管对患者测量的再现性为1.4%(1标准差)。两次测量平均值的入射剂量测定总准确性为1.8%(1标准差)。前野的中心轴入射剂量平均比计算值高1.5%±3.2%(1标准差)。对于后野,差异为0.9%±3.1%(1标准差)。离轴点的偏差稍小,主要是由于计算中对挡块效应的高估。通过测量的入射剂量值外推获得的等中心剂量值与计算值相差0.3%±2.1%。等中心剂量测定的准确性为2%(1标准差)。在校正规定源皮距与实际源皮距的差异后,结果显示与在无不均匀性的聚苯乙烯体模上使用二极管和电离室进行的体模测量结果良好一致。(摘要截断于250字)

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