Bañó M, Simó D, Bellido J, Miravet V, Mechó D, Espín A, Benito F, Renau V
Hospital Gran Vía, Castellón.
Rev Esp Cardiol. 1994 Aug;47(8):529-35.
To determine whether normotensive persons with increases of systolic blood pressure with exercise have left ventricular hypertrophy and/or diastolic disfunction.
A cross-sectional study, using echocardiography as a measurement of left ventricular hypertrophy and diastolic disfunction, was made among healthy population: 53 men, voluntary office workers from a firm and conscript army recruits, aged between 19 and 51 (mean 28, SD = 10.3) who were subjected to the exercise test and the echocardiography.
Twelve people (22.6%) with left ventricular mass index superior to 134 g/m2; and five (9.4%) with a systolic response during exercise higher than 210 mm of Hg. The multiple linear regression showed an association between maximum systolic blood pressure with exercise and the left ventricular mass index in the entire group of subjects (R2 = 18.4%: p < 0.01), but a modification effect with age was detected: no association was found (R2 = 2.8%; p = 0.37) among people under 25 (n = 30), but one was found among the older subjects (R2 = 28.8%; p < 0.01). Diastolic disfunction was associated with age, baseline heart rate and resting diastolic blood pressure (R2 = 64.3%; p < 0.01).
In normotensive subjects, the finding of an exaggerated blood pressure response to exercise could be related to left ventricular hypertrophy.
确定运动时收缩压升高的血压正常者是否存在左心室肥厚和/或舒张功能障碍。
在健康人群中进行了一项横断面研究，使用超声心动图测量左心室肥厚和舒张功能障碍。研究对象为53名男性，包括一家公司的自愿上班族和应征新兵，年龄在19至51岁之间（平均28岁，标准差 = 10.3），他们接受了运动试验和超声心动图检查。
12人（22.6%）左心室质量指数高于134 g/m²；5人（9.4%）运动时收缩压反应高于210 mmHg。多元线性回归显示，在整个研究对象组中，运动时的最大收缩压与左心室质量指数之间存在关联（R² = 18.4%，p < 0.01），但检测到年龄的修正作用：25岁以下人群（n = 30）中未发现关联（R² = 2.8%，p = 0.37），而在年龄较大的受试者中发现了关联（R² = 28.8%，p < 0.01）。舒张功能障碍与年龄、基线心率和静息舒张压相关（R² = 64.3%，p < 0.01）。
在血压正常的受试者中，运动时血压反应过度可能与左心室肥厚有关。
