Kornhauser C, Malacara J M, Donato F, Botello D
Instituto de Investigaciones Médicas, Universidad de Guanajuato, León, México.
Rev Invest Clin. 1994 Jul-Aug;46(4):287-94.
We studied the prevalence of arterial hypertension and its associated risk factors in the urban population of León, State of Guanajuato. Using a cross sectional design we selected by home interview 1000 volunteers 16 to 70 years old from three socioeconomic levels. Forty seven of 468 males (10.0%) and 67 of 532 females (12.6%) were found with hypertension. Increased rates for women were significant (p < 0.01). The rates of hypertension increased slowly with age for men, but for women a sudden increase was found at 48 years of age, the mean age of menopause. At 50 years of age or older, the rate for hypertension was 22.3% for men and 41.7% for women (chi 2 = 7.27, p = 0.007). The multivariate study of factors associated with hypertension showed significance for age, body mass index and smoking habit for the total group and for men, but only age and body weight for women. No association was seen for alcoholism, life style and socioeconomy. A univariate analysis of menopause was strongly associated with hypertension (chi 2 = 46.8, p < 0.0001) and the relative risk for hypertension in menopausal women was 8.04 (7.56-9.73). We conclude that the frequency of hypertension in this urban population is similar to that found in other studies except for women over 50 years of age. Such excess risk of hypertension in this group may be explained by an increased frequency of obesity and an increment in sedentary habits which occur in our female population, and the possible participation of hormone deprivation.
我们研究了瓜纳华托州莱昂市城市人口中动脉高血压的患病率及其相关危险因素。采用横断面设计,我们通过家庭访谈从三个社会经济水平中选取了1000名16至70岁的志愿者。在468名男性中有47名(10.0%),在532名女性中有67名(12.6%)被发现患有高血压。女性患病率的增加具有显著性(p<0.01)。男性高血压患病率随年龄缓慢上升,但女性在48岁(绝经平均年龄)时患病率突然上升。在50岁及以上人群中,男性高血压患病率为22.3%,女性为41.7%(卡方=7.27,p=0.007)。对高血压相关因素的多变量研究表明,年龄、体重指数和吸烟习惯对总体人群和男性具有显著性,但对女性而言只有年龄和体重具有显著性。未发现与酗酒、生活方式和社会经济状况有关联。对绝经情况的单变量分析显示与高血压密切相关(卡方=46.8,p<0.0001),绝经后女性患高血压的相对风险为8.04(7.56 - 9.73)。我们得出结论,除了50岁以上的女性外,该城市人口中高血压的发生率与其他研究结果相似。该组人群中高血压风险过高可能是由于我们女性人群中肥胖发生率增加和久坐习惯增多,以及激素缺乏可能起到的作用。