Macías-Hernández A E, Ortega-González P, Muñoz-Barrett J M, Hernández-Ramos I, Cal y Mayor-Turnbull I, Guerrero-Martínez F J, Gollaz-Mares P G, Hernández-Hernández J, Ponce-de-León-Rosales S
Facultad de Medicina de León, Universidad de Guanajuato, México.
Rev Invest Clin. 1994 Jul-Aug;46(4):295-300.
Hospital-acquired bacteremia is a common cause of morbidity and mortality, mainly in pediatric units. In a 25 month retrospective study, we analyzed the blood cultures from the Hospital General Regional of the city of Leon, Guanajuato State, Mexico, in order to establish the causal agents of nosocomial bacteremia and infer some associations with contaminated intravenous infusion fluids. In addition we performed a two month study to culture the flasks and intravenous tubing used in our infusions. Five hundred and fifty one blood cultures drawn from August 1990 to September 1992 were analyzed. A total of 135 (24.5%) were positive, most of them (51.8%) with strains of the Klebsielleae tribe (SKT) (Klebsiella, Enterobacter, Serratia). The global incidence of bacteremia in the two year period was 4.3%. In the infusion study, 230 intravenous fluids were cultured, with 68 isolates (30%) most from the SKT tribe. A final consideration is made on the role that inadequate management of intravenous liquids could play in the development of endemic and epidemic nosocomial bacteremia in our hospital, and the eventual utility of making cultures of the i.v. liquids.
医院获得性菌血症是发病和死亡的常见原因，主要发生在儿科病房。在一项为期25个月的回顾性研究中，我们分析了墨西哥瓜纳华托州莱昂市综合区域医院的血培养结果，以确定医院获得性菌血症的病原体，并推断与受污染静脉输液的一些关联。此外，我们进行了为期两个月的研究，对输液中使用的烧瓶和静脉输液管进行培养。分析了1990年8月至1992年9月采集的551份血培养标本。共有135份（24.5%）呈阳性，其中大多数（51.8%）为克雷伯菌属（SKT）（克雷伯菌、肠杆菌、沙雷菌）菌株。两年期间菌血症的总体发病率为4.3%。在输液研究中，对230份静脉输液进行了培养，分离出68株（30%），大多数来自SKT菌属。最后考虑了静脉输液管理不当在我院地方性和流行性医院获得性菌血症发生中可能起的作用，以及对静脉输液进行培养的最终效用。
