Edwards K E, Allen J R, Miller M J, Yogev R, Hoffman P C, Klotz R, Marubio S, Burkholder E, Williams T, Davis A T
Pediatrics. 1978 Sep;62(3):304-6.
Enterobacter aerogenes bacteremia associated with the infusion of contaminated admixed intravenous (IV) fluid occurred in seven patients in a pediatric hospital over a five-day period. Clinical illness was characterized by spiking fever in all patients. The temporal clustering of cases allowed for rapid recognition of the problem. The primary control measure was the prompt replacement of the IV fluids, although IV antibiotics were also administered. Hospital pharmacy practices for admixing IV solutions should follow published recommendations to minimize this source of potential contamination of fluids.
在一家儿科医院,5天内有7名患者发生了与输注受污染的混合静脉输液相关的产气肠杆菌菌血症。所有患者的临床症状均以高热为特征。病例的时间聚集性使问题得以迅速识别。主要控制措施是迅速更换静脉输液,尽管也使用了静脉抗生素。医院药房混合静脉输液的操作应遵循已发表的建议,以尽量减少这种潜在的输液污染来源。