Yépez-Muliá L, Ortega-Pierres M G
UIMEIP-Pediatría, Centro Médico Nacional, Siglo XX1-IMSS México, D.F., Mexico.
Rev Latinoam Microbiol. 1994 Apr-Jun;36(2):127-38.
An important approach to the study of trichinellosis is the development of sensitive diagnostic methods that allow the detection of Trichinella spiralis. Recently, ELISA assays that use surface/stichosome and/or secretion/excretion antigens from muscle larvae have been proved to be highly sensitive and specific in the diagnosis of the infection. Furthermore, the high immunodominance of carbohydrate residues on these molecules in a broad host range make them useful diagnostic markers for trichinellosis.
旋毛虫病研究的一个重要方法是开发能够检测旋毛形线虫的灵敏诊断方法。最近，使用来自肌幼虫的表面/杆状体和/或分泌/排泄抗原的酶联免疫吸附测定（ELISA）已被证明在该感染的诊断中具有高度敏感性和特异性。此外，这些分子上碳水化合物残基在广泛宿主范围内具有高度免疫显性，使其成为旋毛虫病有用的诊断标志物。
