Sleep. 1994 Jun;17(4):348-51.
Narcolepsy is a disorder of the central nervous system characterized by excessive sleepiness, cataplexy, and other rapid-eye-movement (REM)-sleep phenomena such as sleep paralysis and hypnagogic hallucinations. Although stimulants are the only effective treatment for the sleepiness of narcolepsy, no clinical guidelines on the use of stimulants in the treatment of narcolepsy have been published that address the following factors: appropriate doses; development of tolerance; potential for side effects, adverse reactions and abuse; and use in children and pregnant or breast-feeding women. These practice parameters from the American Sleep Disorders Association provide the first clinical guidelines on the appropriate use of stimulants in the treatment of narcolepsy.
发作性睡病是一种中枢神经系统紊乱疾病，其特征为过度嗜睡、猝倒，以及其他快速眼动（REM）睡眠现象，如睡眠瘫痪和入睡前幻觉。尽管兴奋剂是治疗发作性睡病嗜睡症状的唯一有效药物，但尚未发布关于在发作性睡病治疗中使用兴奋剂的临床指南来涉及以下因素：合适的剂量；耐受性的发展；副作用、不良反应和滥用的可能性；以及在儿童、孕妇或哺乳期妇女中的使用。美国睡眠障碍协会的这些实践参数提供了关于在发作性睡病治疗中适当使用兴奋剂的首批临床指南。
