Raderer M, Scheithauer W
Department of Internal Medicine I, Vienna University Medical School, Austria.
Scand J Rheumatol. 1994;23(5):291-2. doi: 10.3109/03009749409103732.
The occurrence of a recently discovered musculosceletal pain syndrome, termed postchemotherapy rheumatism, is described in a 52-year-old female who had received adjuvant therapy for ovarian cancer. Although the etiology as well as the pathophysiologic mechanisms of this syndrome remain uncertain, our data support the hypothesis that the alkylating agent cyclophosphamide rather than other chemotherapeutic drugs, corticosteroid withdrawal, or chemically-induced menopause may represent a causal factor.
本文描述了一名52岁接受过卵巢癌辅助治疗的女性患者出现了一种最近发现的肌肉骨骼疼痛综合征，称为化疗后风湿病。尽管该综合征的病因及病理生理机制尚不清楚，但我们的数据支持这样一种假说，即烷化剂环磷酰胺而非其他化疗药物、停用皮质类固醇或化学诱导的绝经可能是一个致病因素。
