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[大鼠实验性高血压中血浆渗出的免疫形态学研究]

[Immunomorphological study of plasmorrhagia in experimental hypertension in rats].

作者信息

Trusov O A

出版信息

Arkh Patol. 1976;38(11):17-22.

PMID:797354
Abstract

Plasmorrhagia of the arterial wall of various organs in rats with ischemic renal, DOCA-saline, and genetic spontaneous hypertension was studied by the method of fluorescent antibodies according to Coombs with the use of pure antibodies to yamma-globudin of a rabbit. The most pronounced plasmorrhagia was observed in rats with DOCA-saline hypertension in the arterial vessels of the kidneys. In rats with genetic hypertension lesions of the heart vessels were noted.

摘要

采用荧光抗体法,根据库姆斯(Coombs)的方法,使用针对兔γ球蛋白的纯抗体,研究了患有缺血性肾性高血压、去氧皮质酮-生理盐水性高血压和遗传性自发性高血压的大鼠各器官动脉壁的血浆渗出情况。在去氧皮质酮-生理盐水性高血压大鼠的肾脏动脉血管中观察到最明显的血浆渗出。在遗传性高血压大鼠中发现了心血管病变。

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