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[内镜超声在胃肠道肿瘤局部区域淋巴结转移检测中的应用]

[Endoscopic ultrasound in detection of locoregional lymph node metastases of gastrointestinal tumors].

作者信息

Nattermann C, Dancygier H

机构信息

Medizinische Klinik II, Städtischen Kliniken Offenbach, Frankfurt/Main.

出版信息

Ultraschall Med. 1994 Aug;15(4):202-6. doi: 10.1055/s-2007-1003965.

Abstract

The locoregional lymph node status was assessed via EUS and CT in 118 patients (37 female, 81 male, average age 63.1 [37-87] years) who had histologically confirmed neoplasias in the upper GI tract. These investigations were made as part of preoperative tumour staging. Resections were performed subsequently, yielding regional lymph node metastases in 76 cases and in 23 patients only enlarged lymph nodes with benign histological findings. Overall accuracy of findings of regional lymph node metastases was 84% for oesophageal carcinomas with EUS and 57% with CT, 78% for gastric carcinomas with EUS and 46% with CT and 68% for pancreatic and ampullary carcinomas with EUS and 53% with CT. In 2 non-Hodgkin lymphomas of the stomach, paragastral malignant lymphomas were identified via EUS but not via CT. In two further cases both methods yielded false positive results. Locoregionally enlarged lymph nodes with exclusively benign histology were found in 22 of 23 cases via EUS but were misinterpreted as metastases in 15 cases. Hence, EUS is evidently superior to CT in identifying locoregional lymph node metastases. The accuracy, however, does not represent tumour status assessment made possible with the help of endosonographic criteria; rather, it is essentially due to the high degree of sensitivity of the method and the scarcity of completely benign enlargements of lymph nodes in the vicinity of neoplasias.

摘要

对118例经组织学确诊为上消化道肿瘤的患者(37例女性,81例男性,平均年龄63.1岁[37 - 87岁]),通过超声内镜(EUS)和计算机断层扫描(CT)评估局部区域淋巴结状态。这些检查作为术前肿瘤分期的一部分进行。随后进行了手术切除,76例出现区域淋巴结转移,23例患者仅发现淋巴结肿大但组织学检查结果为良性。对于食管癌,EUS检测区域淋巴结转移的总体准确率为84%,CT为57%;对于胃癌,EUS为78%,CT为46%;对于胰腺癌和壶腹癌,EUS为68%,CT为53%。在2例胃非霍奇金淋巴瘤中,通过EUS发现了胃旁恶性淋巴瘤,而CT未发现。在另外2例中,两种方法均得出假阳性结果。在23例中有22例通过EUS发现局部区域淋巴结肿大且组织学完全为良性,但其中15例被误诊为转移。因此,在识别局部区域淋巴结转移方面,EUS明显优于CT。然而,其准确率并非借助内镜超声标准进行的肿瘤状态评估;相反,这主要归因于该方法的高灵敏度以及肿瘤附近完全良性的淋巴结肿大较少见。

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