Runkel M, Wenda K, Stelzig A, Rahn B A, Störkel S, Ritter G
Klinik und Poliklinik für Unfallchirurgie, Johannes Gutenberg-Universität Mainz.
Unfallchirurg. 1994 Aug;97(8):385-90.
Experimental findings after unreamed nailing have indicated certain advantages for new bone formation in comparison to reamed nailing. It would be of interest to establish whether any essential differences can be determined in the extent and course of callus formation. To investigate this question, thin sections of bone from 16 tibiae (nailing after transverse osteotomy in sheep) were examined histomorphometrically the progress at the periosteal and interfragmentary surfaces of the remodelling callus being recorded separately after 4, 6 and 8 weeks. After unreamed nailing, more extensive and earlier formation of interfragmentary callus was observed. At 4 weeks postoperatively the remodelled periosteal bone surface was 158 mm2, which was 1.6 times that after the unreamed procedure (95 mm2). By 4 weeks after unreamed nailing the periosteal callus surface was already greater than 6 weeks after reamed nailing. On the basis of these experimental results the use of unreamed nailing can be recommended, especially for open fractures and fractures with severe soft tissue damage.
非扩髓髓内钉固定后的实验结果表明,与扩髓髓内钉固定相比,其在新骨形成方面具有一定优势。确定在骨痂形成的范围和过程中是否存在任何本质差异将是很有意义的。为了研究这个问题,对16只绵羊胫骨干横行截骨后行髓内钉固定的胫骨骨组织薄片进行了组织形态计量学检查,分别记录了术后4周、6周和8周时骨膜表面和骨折断端间骨痂重塑的进展情况。非扩髓髓内钉固定后,观察到骨折断端间骨痂形成更广泛且更早。术后4周时,重塑的骨膜骨表面积为158平方毫米,是扩髓髓内钉固定术后(95平方毫米)的1.6倍。非扩髓髓内钉固定术后4周时,骨膜骨痂表面积已大于扩髓髓内钉固定术后6周时。基于这些实验结果,推荐使用非扩髓髓内钉固定,特别是对于开放性骨折和伴有严重软组织损伤的骨折。