Yang Z F, Yao S Z
Department of Anatomy, Tianjin Medical College.
Sheng Li Xue Bao. 1994 Apr;46(2):187-92.
Intravenous infusion of various doses of Ang II caused significant increases of the salt intake in S-D rats as a result of natriuretic action of the drug. The phenomenon could be abolished by administration of aldosterone but unaffected by adrenalectomy. Captopril could suppress the Ang II effect. Discrepancies with a previous work on the interpretation of the action mode of Ang II were discussed.
静脉注射不同剂量的血管紧张素II会导致S-D大鼠的盐摄入量显著增加,这是该药物利钠作用的结果。这种现象可通过给予醛固酮消除,但不受肾上腺切除术的影响。卡托普利可抑制血管紧张素II的作用。文中讨论了与先前关于血管紧张素II作用模式解释的研究存在的差异。