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[Possible use of the platelet as the cell system for the control of enteropathogenicity of E. coli and of other enterobacteria. Preliminary approach].

作者信息

Fumarola D

出版信息

Boll Ist Sieroter Milan. 1976;55(5):436-42.

PMID:797394
Abstract

After an introduction concerning the assays employed in vitro and in vivo to determine enterotoxigenic activity of E. coli, the A. suggests a new in vitro model as a preliminary approach based upon the influence of LT enterotoxin of Escherichia coli on platelet aggregation (inhibitory effect) as expression of stimulation of adenylatecyclase activity evoked by this fraction and eventually other cholera-like fractions released from enterobacteria.

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