Fumarola D
Boll Ist Sieroter Milan. 1976;55(5):436-42.
After an introduction concerning the assays employed in vitro and in vivo to determine enterotoxigenic activity of E. coli, the A. suggests a new in vitro model as a preliminary approach based upon the influence of LT enterotoxin of Escherichia coli on platelet aggregation (inhibitory effect) as expression of stimulation of adenylatecyclase activity evoked by this fraction and eventually other cholera-like fractions released from enterobacteria.
在介绍了用于体外和体内测定大肠杆菌产肠毒素活性的试验之后,作者提出了一种新的体外模型作为初步方法,该模型基于大肠杆菌的LT肠毒素对血小板聚集的影响(抑制作用),以此作为该组分以及最终从肠道细菌释放的其他霍乱样组分所引发的腺苷酸环化酶活性刺激的表达。