移植性骨髓性白血病大鼠血源性单核细胞的起源与作用
The origin and role of blood-borne monocytes in rats with a transplanted myelogenous leukaemia.
作者信息
Gauci C L, Wrathmell A, Alexander P
出版信息
Cancer Lett. 1975 Sep;1(1):33-7. doi: 10.1016/s0304-3835(75)94893-4.
PMID:797440
Abstract
The growth of a transplantable myeloid leukaemia into its syngeneic host is accompanied by a progressive increase in the number of blood monocytes. These were shown to be of host origin and were not derived from the inoculated leukaemia cells. The host response which is responsible for the monocytosis differs from that associated with the entry of monocytes into immunogenic sarcomas.
摘要
可移植性髓性白血病在其同基因宿主体内生长时，血液单核细胞数量会逐渐增加。这些单核细胞显示为宿主来源，并非来自接种的白血病细胞。导致单核细胞增多的宿主反应不同于与单核细胞进入免疫原性肉瘤相关的反应。
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