Dijkstra T, Barkema H W, van Buuren R D, van Spanje J G, Jorritsma H
Gezondheidsdienst voor Dieren in Noord-Nederland, Drachten.
Tijdschr Diergeneeskd. 1994 Nov 1;119(21):634-6.
Sixteen dairy cows with chronic puerperal endometritis between 3 and 8 weeks post partum were treated with intra-uterine applied oxytetracycline (OTC) and lugol. OTC was rapidly removed from plasma and was not detectable after 48 hours. The concentration of OTC in milk did not exceed 40 micrograms/kg, and it was still detectable in milk 34 hours after treatment. The concentration of OTC in milk was always lower than the limit of 50 micrograms/kg used by milk-testing stations and the European limit (MRL) of 100 micrograms/kg. Milk from cows treated with lugol did not cause inhibition in the plate test.
16头产后3至8周患有慢性产后子宫内膜炎的奶牛接受了宫内注射土霉素(OTC)和卢戈氏碘液的治疗。土霉素从血浆中迅速清除,48小时后无法检测到。牛奶中土霉素的浓度不超过40微克/千克,治疗后34小时仍可在牛奶中检测到。牛奶中土霉素的浓度始终低于牛奶检测站使用的50微克/千克的限值以及欧洲100微克/千克的限量(MRL)。用卢戈氏碘液治疗的奶牛产的牛奶在平板试验中未产生抑制作用。