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[通过乳胶凝集法测定阿片类药物]

[The determination of opiates by latex agglutination].

作者信息

Miagkova M A, Zapol'skaia E B, Zapol'skiĭ M E, Gritskova I A, Chirikova O V

出版信息

Sud Med Ekspert. 1994 Jul-Sep;37(3):23-5.

PMID:7974607
Abstract

A method based on latex agglutination test has been developed for detection of opiates in human urine. Specific reagents were synthesized and conditions of interaction of conjugated latex antigens with specific antibodies to morphine in the presence of an inhibitor were examined. Sensitivity of the method was 100 ng/ml. The developed latex agglutination test for detection of opiates may be used in combination with enzyme immunoassay in practical forensic medicine and narcology.

摘要

已开发出一种基于乳胶凝集试验的方法用于检测人尿中的阿片类物质。合成了特异性试剂,并研究了在抑制剂存在下共轭乳胶抗原与吗啡特异性抗体的相互作用条件。该方法的灵敏度为100 ng/ml。所开发的用于检测阿片类物质的乳胶凝集试验可在实际法医学和麻醉学中与酶免疫测定法联合使用。

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