细菌与药物：20世纪90年代的抗生素耐药性
Bugs and drugs: antibiotic resistance in the 1990s.
作者信息
Rickman L S
出版信息
Todays OR Nurse. 1994 Sep-Oct;16(5):7-12.
PMID:7974655
Abstract
- Bacteria have been versatile in circumventing the mechanisms by which antibiotics work; in the 1990s there has been a world-wide resurgence of antibiotic-resistant bacterial diseases. 2. Resistance to certain antibiotics develops in bacteria through three basic processes: mutation, transduction, and conjugation. 3. Infection-control programs, if combined with intensive infection-control measures and control of antibiotic use, may be effective at reducing the transmission of resistant pathogens.
摘要
- 细菌在规避抗生素作用机制方面手段多样；在20世纪90年代，耐药细菌性疾病在全球范围内再度出现。2. 细菌对某些抗生素产生耐药性有三个基本过程：突变、转导和接合。3. 感染控制计划若与强化感染控制措施及抗生素使用控制相结合，可能有效减少耐药病原体的传播。
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