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Hypoxia impairs cellular differentiation.

作者信息

Tannen R L, Sahai A

机构信息

Department of Medicine, University of Southern California, Los Angeles.

出版信息

Trans Am Clin Climatol Assoc. 1994;105:111-7; discussion 118-9.

PMID:7974963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2376740/
Abstract
摘要

相似文献

1
Hypoxia impairs cellular differentiation.缺氧会损害细胞分化。
Trans Am Clin Climatol Assoc. 1994;105:111-7; discussion 118-9.
2
Chronic hypoxia induces LLC-PK1 cell proliferation and dedifferentiation by the activation of protein kinase C.
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3
Chronic hypoxia impairs the differentiation of 3T3-L1 fibroblast in culture: role of sustained protein kinase C activation.
J Cell Physiol. 1994 Jul;160(1):107-12. doi: 10.1002/jcp.1041600113.
4
Heat shock protein 70 overexpression protects LLC-PK1 tubular cells from heat shock but not hypoxia.热休克蛋白70的过表达可保护LLC - PK1肾小管细胞免受热休克损伤，但不能保护其免受缺氧损伤。
Kidney Int. 1999 Jan;55(1):189-97. doi: 10.1046/j.1523-1755.1999.00251.x.
5
Chronic exposure of LLC-PK1 epithelia to the phorbol ester TPA produces polyp-like foci with leaky tight junctions and altered protein kinase C-alpha expression and localization.LLC-PK1上皮细胞长期暴露于佛波酯TPA会产生具有紧密连接渗漏、蛋白激酶C-α表达和定位改变的息肉样病灶。
Exp Cell Res. 1996 Aug 25;227(1):12-22. doi: 10.1006/excr.1996.0244.
6
Subcellular localization of S100A11 (S100C) in LLC-PK1 renal cells: Calcium- and protein kinase c-dependent association of S100A11 with S100B and vimentin intermediate filaments.S100A11（S100C）在LLC-PK1肾细胞中的亚细胞定位：S100A11与S100B及波形蛋白中间丝的钙和蛋白激酶C依赖性结合。
Microsc Res Tech. 2003 Apr 15;60(6):639-51. doi: 10.1002/jemt.10305.
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Regulation of organic cation transport in IHKE-1 and LLC-PK1 cells. Fluorometric studies with 4-(4-dimethylaminostyryl)-N-methylpyridinium.IHKE-1和LLC-PK1细胞中有机阳离子转运的调节。用4-(4-二甲基氨基苯乙烯基)-N-甲基吡啶鎓进行荧光研究。
J Pharmacol Exp Ther. 1998 Jul;286(1):305-10.
8
Distinct localizations of tropomyosin isoforms in LLC-PK1 epithelial cells suggests specialized function at cell-cell adhesions.原肌球蛋白亚型在LLC-PK1上皮细胞中的不同定位表明其在细胞间黏附中具有特殊功能。
Cell Motil Cytoskeleton. 1998;40(4):393-407. doi: 10.1002/(SICI)1097-0169(1998)40:4<393::AID-CM7>3.0.CO;2-C.
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Parathyroid hormone (PTH)/PTH-related peptide receptor density modulates activation of phospholipase C and phosphate transport by PTH in LLC-PK1 cells.甲状旁腺激素（PTH）/PTH相关肽受体密度调节LLC-PK1细胞中PTH对磷脂酶C的激活及磷酸盐转运。
Endocrinology. 1995 Sep;136(9):3884-91. doi: 10.1210/endo.136.9.7649096.
10
Evaluation of proliferation and functional differentiation of LLC-PK1 cells on porous polymer membranes for the development of a bioartificial renal tubule device.用于生物人工肾小管装置开发的多孔聚合物膜上LLC-PK1细胞增殖和功能分化的评估。
Tissue Eng. 2005 Sep-Oct;11(9-10):1506-15. doi: 10.1089/ten.2005.11.1506.

本文引用的文献

1
Proliferating and quiescent cells exhibit different subcellular distribution of protein kinase C activity.增殖细胞和静止细胞表现出蛋白激酶C活性的不同亚细胞分布。
FEBS Lett. 1986 Jan 20;195(1-2):352-6. doi: 10.1016/0014-5793(86)80192-2.
2
Induction of mitochondrial metabolism and pH-modulated ammoniagenesis by rocking LLC-PK1 cells.摇晃 LLC-PK1 细胞诱导线粒体代谢和 pH 调节的氨生成
Am J Physiol. 1986 Aug;251(2 Pt 1):C293-8. doi: 10.1152/ajpcell.1986.251.2.C293.
3
Possible involvement of protein kinase C in proliferation and differentiation of osteoblast-like cells.
FEBS Lett. 1989 Jan 30;243(2):183-5. doi: 10.1016/0014-5793(89)80126-7.
4
Rocking promotes differentiated properties in LLC-PK cells by improved oxygenation.摇摆通过改善氧合作用促进LLC-PK细胞的分化特性。
Am J Physiol. 1989 May;256(5 Pt 1):C1064-9. doi: 10.1152/ajpcell.1989.256.5.C1064.
5
Studies and prospectives of the protein kinase c family for cellular regulation.蛋白激酶C家族对细胞调节的研究及展望
Cancer. 1989 May 15;63(10):1892-903. doi: 10.1002/1097-0142(19890515)63:10<1892::aid-cncr2820631005>3.0.co;2-z.
6
Sustained activation of protein kinase C is essential to HL-60 cell differentiation to macrophage.蛋白激酶C的持续激活对于HL-60细胞分化为巨噬细胞至关重要。
Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11062-6. doi: 10.1073/pnas.88.24.11062.
7
Differential expression of PKC isoforms and PC12 cell differentiation.
Exp Cell Res. 1992 Mar;199(1):111-9. doi: 10.1016/0014-4827(92)90468-n.
8
The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation.蛋白激酶C同工酶在细胞增殖和分化调控中的作用。
J Cell Sci. 1992 Dec;103 ( Pt 4):881-7. doi: 10.1242/jcs.103.4.881.
9
Hypoxia-mediated impaired differentiation by LLC-PK1 cells: evidence based on the protein kinase C profile.缺氧介导的LLC-PK1细胞分化受损：基于蛋白激酶C谱的证据
Kidney Int. 1992 Nov;42(5):1145-52. doi: 10.1038/ki.1992.398.
10
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C.通过磷脂水解和蛋白激酶C激活进行的细胞内信号传导。
Science. 1992 Oct 23;258(5082):607-14. doi: 10.1126/science.1411571.