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用牛γ-干扰素检测法在皮肤试验阴性牛中检测牛分枝杆菌感染

Detection of Mycobacterium bovis infection in skin test-negative cattle with an assay for bovine interferon-gamma.

作者信息

Neill S D, Cassidy J, Hanna J, Mackie D P, Pollock J M, Clements A, Walton E, Bryson D G

机构信息

Veterinary Sciences Division, Department of Agriculture, Belfast.

出版信息

Vet Rec. 1994 Aug 6;135(6):134-5. doi: 10.1136/vr.135.6.134.

DOI:10.1136/vr.135.6.134
PMID:7975105
Abstract

Mycobacterium bovis was isolated from respiratory secretions and lymph nodes from 15 skin test-negative cattle which exhibited interferon-gamma responses. These field cases, identified by blood testing, constituted a significant proportion of skin test-negative cattle which had been subjected to extensive post mortem examinations. Typical tuberculous lesions were found in seven of them. The consequences of cattle with early tuberculosis infection not being detected by traditional tuberculin testing are considered.

摘要

从15头皮肤试验阴性但出现γ干扰素反应的牛的呼吸道分泌物和淋巴结中分离出牛分枝杆菌。通过血液检测确定的这些现场病例,在接受广泛尸检的皮肤试验阴性牛中占相当大的比例。其中7头牛发现有典型的结核病变。文中考虑了早期结核感染的牛未被传统结核菌素检测发现的后果。

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