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[热量摄入减少对老年大鼠气体交换和产热昼夜节律的影响]

[Effect of reduced caloric intake on circadian rhythm of gas exchange and heat production in old rats].

作者信息

Muradian Kh K, Shinkar E I

出版信息

Vopr Pitan. 1993 May-Jun(3):33-6.

PMID:7975426
Abstract

Fifty male Wistar rats at the age of 24 months were divided into two equal groups (test and control). Test animals received a 2-fold reduced ration. At the age of 32 months all the animals were examined for gas exchange and heat production circadian rhythm. The test animals were 3 hours fast compared to controls in maximal values of gas exchange, rectal temperature and heat conductivity, while relevant mean daily values did not change. The circadian rhythm of the above values in test animals corresponded to that of younger rats indicating higher performance of the underlying mechanisms and explaining longer survival of the test rats, who had less rates of gas exchange and rectal temperature variability and lower heat circulation coefficient.

摘要

50只24月龄的雄性Wistar大鼠被分为两组(试验组和对照组),每组数量相等。试验组动物的食量减少了一半。在32月龄时,对所有动物进行气体交换和产热昼夜节律的检测。试验组动物在气体交换、直肠温度和热导率的最大值方面比对照组禁食3小时,而相关的每日平均值没有变化。试验组动物上述指标的昼夜节律与年轻大鼠的相似,这表明其潜在机制的性能更高,也解释了试验组大鼠存活率更高的原因,它们的气体交换和直肠温度变异性较低,热循环系数也较低。

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