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[卵巢癌与女性上生殖道同时性原发性癌]

[Ovarian cancers and simultaneous primary cancers of the upper female genital tract].

作者信息

Maassen V, Debus-Thiede G

机构信息

I. Frauenklinik, Universität München.

出版信息

Zentralbl Gynakol. 1994;116(9):527-30.

PMID:7975964
Abstract

258 patients with ovarian carcinomas who underwent surgery at the University Women's Hospital Charlottenburg/Berlin (during 1980-1987) and at the I. University Women's Hospital Munich (during 1987-1990) were re-examined for the occurrence of a simultaneous primary secondary carcinoma in the upper genital tract. The diagnoses were made according to strict histological criteria. In 13 cases (5%) simultaneous carcinomas of the upper genital tract were found. In this group we would like to especially mention 6 of the 33 patients (18.2%) with an endometroid ovarian carcinoma, 3 of the 47 patients (6.4%) with an ovarian tumor of low malignant potential and 1 of the 12 patients with a serous-papillary carcinoma of the peritoneum ("non-ovarian carcinoma of the ovary"). In our opinion these carcinomas are independent multifocal primaries originating from the primary and secondary Mullerian epithelium. Staging protocols of these simultaneous tumors, especially prognostic estimation and development of therapeutic strategies should consider this possible multifocal pathogenesis.

摘要

对1980年至1987年间在柏林夏洛滕堡大学妇女医院以及1987年至1990年间在慕尼黑第一大学妇女医院接受手术的258例卵巢癌患者进行了复查,以确定上生殖道是否存在同时性原发性和继发性癌。诊断依据严格的组织学标准。共发现13例(5%)上生殖道同时性癌。在这组病例中,我们特别要提及33例子宫内膜样卵巢癌患者中的6例(18.2%)、47例低恶性潜能卵巢肿瘤患者中的3例(6.4%)以及12例腹膜浆液性乳头状癌患者(“卵巢非卵巢癌”)中的1例。我们认为这些癌是起源于原发性和继发性苗勒上皮的独立多灶性原发性肿瘤。这些同时性肿瘤的分期方案,尤其是预后评估和治疗策略的制定,应考虑到这种可能的多灶性发病机制。

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