Dahlstrøm B L, Nesheim B I
Department of Obstetrics and Gynecology, Akershus Central Hospital, Nordbyhagen, Norway.
Acta Obstet Gynecol Scand. 1994 Oct;73(9):695-7. doi: 10.3109/00016349409029405.
Thrombocytopenia in pregnancy, during and after delivery can be an indicator of serious preeclampsia or any condition accompanied by disseminated intravascular coagulation (DIC). In order to recognize thrombocytopenia, it is important to know the expected platelet count in healthy women. Literature search gave no information regarding changes of platelet count in healthy women shortly after uneventful pregnancies and uncomplicated deliveries, either vaginal or cesarean section. The intention of this study was to investigate whether there were any such changes.
Blood samples were taken on admission to the obstetric ward, first and third day after vaginal delivery (11 patients) or cesarean section (11 patients). Platelet count, hemoglobin concentration and hematocrit was measured for each blood sample.
There was no significant change in platelet count after vaginal delivery. Following cesarean section there was a median decrease in platelet count of 12.5% the first postoperative day, and a median increase of 5% the third postoperative day.
Platelet count remains unchanged after uncomplicated vaginal delivery. Shortly following normal pregnancy and uncomplicated cesarean section platelets should be expected to decrease slightly.
孕期、分娩期间及分娩后出现的血小板减少可能是重度子痫前期或任何伴有弥散性血管内凝血(DIC)病症的一个指标。为了识别血小板减少,了解健康女性的预期血小板计数很重要。文献检索未获得关于正常妊娠及顺产或剖宫产术后短期内健康女性血小板计数变化的相关信息。本研究旨在调查是否存在此类变化。
在产科病房入院时、阴道分娩(11例患者)或剖宫产(11例患者)后的第一天和第三天采集血样。对每份血样进行血小板计数、血红蛋白浓度和血细胞比容测定。
阴道分娩后血小板计数无显著变化。剖宫产术后第一天血小板计数中位数下降12.5%,术后第三天中位数上升5%。
顺产无并发症时血小板计数保持不变。正常妊娠及剖宫产无并发症后短期内血小板计数预计会略有下降。