van den Helder C J, Hage J J
Department of Plastic and Reconstructive Surgery, Academic Hospital of the Free University, Amsterdam, The Netherlands.
Aesthetic Plast Surg. 1994 Summer;18(3):307-13. doi: 10.1007/BF00449800.
The wish to prevent or improve scars, whether they are of surgical or traumatic origin, has led to the development of scar creams and gels that are said to influence the aesthetic appearance of a scar. In this article the literature on results of the topical application of various scar creams and gels is reviewed. It is concluded that no single modality has been proven to manage hypertrophic scarring except maybe silicone and BAPN. Further research into the physiology and pharmacophysiology of scar tissue is needed. With respect to scars, it still applies that even "plastic surgeons can't erase without a trace."
预防或改善疤痕的愿望,无论其源于手术还是外伤,都促使了疤痕霜和凝胶的研发,据说这些产品会影响疤痕的美观。本文回顾了有关各种疤痕霜和凝胶局部应用效果的文献。得出的结论是,除了硅酮和β-氨基丙腈或许外,没有单一的方法已被证明可有效治疗增生性疤痕。需要对疤痕组织的生理学和药理生理学进行进一步研究。关于疤痕,仍然适用的是,即使“整形外科医生也无法完全消除痕迹”。