Quam D A
Kaiser Permanente Hospital, Fontana, California.
Am Fam Physician. 1994 Nov 15;50(7):1491-6.
Although the incidence of Reye's syndrome is declining, it remains a deadly disease. Early recognition and initiation of supportive measures can decrease the mortality rate from this disorder. Glucose levels should be maintained and electrolyte imbalances and coagulopathies should be corrected in patients with early Reye's syndrome. Comatose patients require specialized care at a tertiary care facility that has the capability to prevent and treat intracranial hypertension. Survivors of Reye's syndrome may have subtle neuropsychologic deficits but generally recover very well considering the gravity of the disease.
尽管瑞氏综合征的发病率在下降,但它仍然是一种致命疾病。早期识别并启动支持性措施可降低这种疾病的死亡率。对于早期瑞氏综合征患者,应维持血糖水平,纠正电解质失衡和凝血病。昏迷患者需要在具备预防和治疗颅内高压能力的三级医疗机构接受专科护理。瑞氏综合征的幸存者可能存在轻微的神经心理缺陷,但考虑到该疾病的严重性,总体恢复情况良好。