Woods M S, Shellito J L, Santoscoy G S, Hagan R C, Kilgore W R, Traverso L W, Kozarek R A, Brandabur J J
Department of Surgery, Wichita Clinic, Kansas 67208.
Am J Surg. 1994 Dec;168(6):560-3; discussion 563-5. doi: 10.1016/s0002-9610(05)80122-9.
Cystic duct leak (CDL) appears to complicate laparoscopic cholecystectomy (LC) more often than open cholecystectomy (OC). No mention of CDL was found in a literature review that covered 48,822 OCs and their complications.
Fifty-four patients who developed biliary tract injuries following LC were reviewed for: the time from LC to presentation, presenting symptoms, method of diagnosis, treatment, outcome, and follow-up.
Seventeen of 54 biliary tract complications (31%) were CDLs. The CDLs presented at a median of 4 days after LC with pain (76%) and nausea and/or vomiting (35%). Endoscopic retrograde cholangiopancreatography (ERCP) defined the diagnosis and the anatomy of the leak in 11 patients (65%). Biliary endoprosthesis placement was employed in 8 patients, with concomitant sphincterotomy in 5 (63%), and resolved CDL in every case. Seven (88%) of these patients were asymptomatic at a median interval of 10 months after stent retrieval. Six patients (35%) underwent reoperation. Five had laparotomy with ligation of the cystic duct stump and 1 underwent laparoscopic examination with reclipping of the cystic duct stump. Five (83%) were asymptomatic at a median follow-up of 26 months. CDLs may result from inaccurate clip placement, perforations proximal to the clips, and stump necrosis, as documented at reoperation.
CDLs occur more frequently in LC than in the OCs reported in the literature. Most leaks require intervention. ERCP with stent placement is the diagnostic and therapeutic procedure of choice and has a high success rate of resolving leaks. To forestall CDLs, it is important to place clips accurately and avoid electrocautery in the vicinity of the cystic duct.
与开腹胆囊切除术(OC)相比,胆囊管漏(CDL)似乎更常使腹腔镜胆囊切除术(LC)复杂化。在一项涵盖48,822例OC及其并发症的文献综述中未提及CDL。
对54例LC术后发生胆道损伤的患者进行回顾,内容包括:从LC至就诊的时间、临床表现、诊断方法、治疗、结局及随访情况。
54例胆道并发症中有17例(31%)为CDL。CDL多在LC术后4天出现,表现为疼痛(76%)、恶心和/或呕吐(35%)。内镜逆行胰胆管造影(ERCP)明确了11例患者(65%)漏口的诊断及解剖结构。8例患者采用了胆道内支架置入术,其中5例(63%)同时行括约肌切开术,所有病例的CDL均得到解决。这些患者中有7例(88%)在取出支架后中位间隔10个月时无症状。6例患者(35%)接受了再次手术。5例行开腹手术结扎胆囊管残端,1例行腹腔镜检查重新夹闭胆囊管残端。5例(83%)在中位随访26个月时无症状。再次手术证实,CDL可能由夹子放置不准确、夹子近端穿孔及残端坏死引起。
LC中CDL的发生率高于文献报道的OC。大多数漏口需要干预。ERCP联合支架置入是诊断和治疗的首选方法,解决漏口的成功率很高。为预防CDL,准确放置夹子并避免在胆囊管附近进行电灼很重要。