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胰管未扩张患者中行胰管空肠吻合术的作用。

The role of pancreatojejunostomy in patients without dilated pancreatic ducts.

作者信息

Delcore R, Rodriguez F J, Thomas J H, Forster J, Hermreck A S

机构信息

Department of Surgery, University of Kansas Medical Center, Kansas City 66160-7309.

出版信息

Am J Surg. 1994 Dec;168(6):598-601; discussion 601-2. doi: 10.1016/s0002-9610(05)80129-1.

Abstract

OBJECTIVE

To determine the safety and efficacy of longitudinal pancreatojejunostomy in patients with chronic pancreatitis and intractable pain who do not have a markedly dilated pancreatic duct.

BACKGROUND

Ductal decompression by side-to-side, longitudinal pancreatojejunostomy has become the operation of choice for patients with chronic pancreatitis and intractable pain when the pancreatic duct is markedly dilated. However, markedly dilated pancreatic ducts are found in less than 40% of patients with disabling pain.

PATIENTS AND METHODS

Twenty-eight consecutive patients with intractable pain from chronic pancreatitis, most of whom had minimal or no dilation of the pancreatic duct, were treated with side-to-side, longitudinal pancreatojejunostomy between 1970 and 1993.

RESULTS

There were 18 (64%) males and 10 (36%) females. The mean age was 41 years (range 11 to 72). The etiologies for chronic pancreatitis were alcohol (82%), gallstones (7%), trauma (7%), and familial trait (4%). Intractable pain was present for a mean of 4 years (range 0.5 to 12). Thirteen patients (46%) were dependent on narcotics prior to surgery. Twenty-five patients (89%) had minimal (< 8 mm) or no dilation of the pancreatic duct and 3 (11%) had markedly dilated pancreatic ducts (> 10 mm). All experienced complete pain relief in the immediate postoperative period. Twenty-four patients (86%) have remained free of pain after a mean follow-up of 3.5 years (range 1 to 8).

CONCLUSIONS

In patients with chronic pancreatitis and intractable pain, small pancreatic duct size should not be considered a contraindication to side-to-side, longitudinal pancreatojejunostomy.

摘要

目的

确定在慢性胰腺炎且疼痛顽固但胰管无明显扩张的患者中行纵向胰空肠吻合术的安全性和有效性。

背景

对于慢性胰腺炎且疼痛顽固、胰管明显扩张的患者,侧侧纵向胰空肠吻合术进行导管减压已成为首选手术方式。然而,在导致功能障碍性疼痛的患者中,发现胰管明显扩张的不到40%。

患者与方法

1970年至1993年间,对28例因慢性胰腺炎导致顽固性疼痛的连续患者进行了侧侧纵向胰空肠吻合术治疗,这些患者大多数胰管仅有轻微扩张或无扩张。

结果

男性18例(64%),女性10例(36%)。平均年龄41岁(范围11至72岁)。慢性胰腺炎的病因包括酒精(82%)、胆结石(7%)、创伤(7%)和家族性特征(4%)。顽固性疼痛平均持续4年(范围0.5至12年)。13例患者(46%)术前依赖麻醉药品。25例患者(89%)胰管仅有轻微扩张(< 8 mm)或无扩张,3例(11%)胰管明显扩张(> 10 mm)。所有患者术后即刻疼痛完全缓解。平均随访3.5年(范围1至8年)后,24例患者(86%)仍无疼痛。

结论

对于慢性胰腺炎且疼痛顽固的患者,胰管细小不应被视为侧侧纵向胰空肠吻合术的禁忌证。

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