涉及妊娠产物的母体恶性肿瘤：恶性黑色素瘤和髓母细胞瘤的报告。
Maternal malignancy involving the products of conception: a report of malignant melanoma and medulloblastoma.
作者信息
Brossard J, Abish S, Bernstein M L, Baruchel S, Kovacs L, Pollack R
机构信息
Department of Pediatrics, Centre Hospitalier Universitaire-Sherbrooke, University of Sherbrooke, Quebec, Canada.
出版信息
Am J Pediatr Hematol Oncol. 1994 Nov;16(4):380-3.
PURPOSE
Cancer in pregnancy is not uncommon, but cases of maternal malignancy involving the placenta or the fetus are much more rare. We report two additional cases.
PATIENTS AND METHODS
We report one case of malignant melanoma discovered during pregnancy and found to have metastasized to the placenta. We also describe a case of maternal medulloblastoma involving the placenta at delivery.
CONCLUSIONS
Although maternal malignancy during pregnancy occurs in as many as one in 1,000 pregnancies, involvement of the products of conception is rare. Subsequent malignancy in the fetus is even more rare. We report two cases, one of melanoma and another of medulloblastoma (the first such case described). Both infants are alive and well.
目的
妊娠期癌症并不罕见，但涉及胎盘或胎儿的母体恶性肿瘤病例则更为罕见。我们报告另外两例病例。
患者与方法
我们报告一例在孕期发现并已转移至胎盘的恶性黑色素瘤病例。我们还描述了一例在分娩时涉及胎盘的母体髓母细胞瘤病例。
结论
尽管孕期母体恶性肿瘤在多达千分之一的妊娠中发生，但累及妊娠产物的情况罕见。胎儿随后发生恶性肿瘤的情况更为罕见。我们报告两例病例，一例为黑色素瘤，另一例为髓母细胞瘤（首例此类病例）。两名婴儿均存活且状况良好。
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