Peck S, Peck L, Kataja M
Harvard School of Dental Medicine, Boston, MA.
Angle Orthod. 1994;64(4):249-56. doi: 10.1043/0003-3219(1994)064<0249:WNID>2.0.CO;2.
Palatal displacement of the maxillary canine tooth is a positional variation thought generally to develop as a result of local factors, such as retained deciduous canines, anomalous permanent lateral incisors, or dental crowding. This article contributes biologic evidence pointing to genetic factors as the primary origin of most palatal displacements and subsequent impactions of maxillary canine teeth. Data gathered from multiple sources are integrated to support a genetic etiology for the palatally displaced canine (PDC) on the basis of five evidential categories: 1. Occurrence of other dental anomalies concomitant with PDC; 2. Bilateral occurrence of PDC; 3. Sex differences in PDC occurrence; 4. Familial occurrence of PDC; 5. Population differences in PDC occurrence. From analysis of available evidence, the PDC positional anomaly appears to be a product of polygenic, multifactorial inheritance.
上颌尖牙腭向移位是一种位置变异，通常被认为是由局部因素引起的，如乳牙滞留、恒牙侧切牙异常或牙列拥挤。本文提供了生物学证据，表明遗传因素是大多数上颌尖牙腭向移位及随后阻生的主要原因。从多个来源收集的数据被整合起来，基于五类证据支持腭向移位尖牙（PDC）的遗传病因：1. 与PDC同时出现的其他牙齿异常；2. PDC的双侧出现；3. PDC出现的性别差异；4. PDC的家族性出现；5. PDC出现的人群差异。通过对现有证据的分析，PDC位置异常似乎是多基因、多因素遗传的产物。
