Zicker S C, Spensley M S, Rogers Q R, Willits N H
Department of Medicine, School of Veterinary Medicine, University of California, Davis 95616.
Am J Vet Res. 1991 Jul;52(7):1010-3.
Concentrations of amino acids in the plasma of 13 neonatal foals with septicemia were compared with the concentrations of amino acids in the plasma of 13 age-matched neonatal foals without septicemia. Analysis of the results revealed significantly lower concentrations of arginine, citrulline, isoleucine, proline, threonine, and valine in the plasma of foals with septicemia. The ratio of the plasma concentrations of the branched chain amino acids (isoleucine, leucine, and valine) to the aromatic amino acids (phenylalanine and tyrosine), was also significantly lower in the foals with septicemia. In addition, the concentrations of alanine, glycine, and phenylalanine were significantly higher in the plasma of foals with septicemia. Therefore, neonatal foals with septicemia had significant differences in the concentrations of several amino acids in their plasma, compared with concentrations from healthy foals. These differences were compatible with protein calorie inadequacy and may be related to an alteration in the intake, production, use, or clearance of amino acids from the plasma pool in sepsis.
将13匹患败血症新生马驹血浆中的氨基酸浓度与13匹年龄匹配的未患败血症新生马驹血浆中的氨基酸浓度进行了比较。结果分析显示，患败血症马驹血浆中的精氨酸、瓜氨酸、异亮氨酸、脯氨酸、苏氨酸和缬氨酸浓度显著降低。患败血症马驹血浆中支链氨基酸（异亮氨酸、亮氨酸和缬氨酸）与芳香族氨基酸（苯丙氨酸和酪氨酸）的浓度比也显著降低。此外，患败血症马驹血浆中的丙氨酸、甘氨酸和苯丙氨酸浓度显著更高。因此，与健康马驹相比，患败血症的新生马驹血浆中几种氨基酸的浓度存在显著差异。这些差异与蛋白质热量不足相符，可能与败血症时血浆池中氨基酸的摄入、产生、使用或清除改变有关。
