Perry R L, Williams J F, Carrig C B, Kaneene J B, Schillhorn van Veen T W
Department of Small Animal Clinical Sciences, Michigan State University, East Lansing 48824.
Am J Vet Res. 1994 Aug;55(8):1120-6.
In rats infected with the cestode Taenia taeniaeformis, hepatomegaly results from development of parasitic cysts in the liver. Diffuse nodular mucosal hyperplasia in the glandular region (corpus and antrum) of the stomach, and gross thickening of the intestinal mucosa also result. Between postinfection days (PID) 21 and 84, radiologic observations were made after oral administration of a barium sulfate suspension in T taeniaeformis-infected rats and in age/sex-matched controls. There was radiographic evidence of hepatic enlargement at PID 21. Enlargement of the gastric folds was first observed along the greater curvature of the stomach at PID 35. Fimbriation of small intestinal mucosal surfaces resulted from thickening of the intestinal villi and was observed in the duodenum at PID 21. Intestinal motility was assessed, and contractions were counted, using image intensification fluoroscopy, then were recorded on videotape. There were no significant differences between control and infected rats for gastric emptying time, intestinal transit time, and number of intestinal contractions per minute. Barium contrast radiography clearly indicated large gastric folds, thickening of the small intestinal villi, and hepatic enlargement, and was useful for assessing gastrointestinal motility.
在感染绦虫——泡状带绦虫的大鼠中，肝脏肿大是由肝脏中寄生囊肿的形成所致。胃的腺区（胃体和胃窦）出现弥漫性结节状黏膜增生，肠道黏膜也出现明显增厚。在感染后第21天至84天期间，给感染泡状带绦虫的大鼠以及年龄/性别匹配的对照大鼠口服硫酸钡混悬液后进行放射学观察。在感染后第21天有肝脏肿大的放射学证据。在感染后第35天首次观察到胃皱襞沿胃大弯处增大。小肠黏膜表面的绒毛状改变是由肠绒毛增厚引起的，在感染后第21天于十二指肠观察到。使用影像增强荧光透视法评估肠道蠕动并计数收缩次数，然后记录在录像带上。对照大鼠和感染大鼠在胃排空时间、肠道通过时间以及每分钟肠道收缩次数方面没有显著差异。钡剂造影清楚地显示出大的胃皱襞、小肠绒毛增厚以及肝脏肿大，并且对于评估胃肠动力很有用。
