Heether J, Whalen T, Doolin E
Robert Wood Johnson Medical School at Camden, New Jersey.
Am Surg. 1994 Nov;60(11):840-1.
Our purpose was to determine the natural history of unresectable lymphangiomas. From 1986-1992, 11 cases of unresectable lymphangiomas were seen in our institution (age 1 month to 14 years). Locations affected included cervical (8), mediastinal (6), and abdominal (3). Presenting symptoms included abdominal pain, respiratory problems, chylothorax, pleural effusions, and pneumococcal sepsis. Attempts at total excision were performed in all but one patient who had biopsy only. The tumor that could not be removed was then observed for the development of complications. Follow-up of these 11 patients ranged from 2 to 6 years. Two have completely regressed, five have stabilized, and four have required repeat operation. Of the five that have stabilized, none have developed complications such as infection or compression secondary to the mass. In an asymptomatic patient, it appears that the portion of the lymphangiomas remaining will regress or at least not progress, and no further resections were required.
我们的目的是确定不可切除性淋巴管瘤的自然病程。1986年至1992年期间，我们机构共收治了11例不可切除性淋巴管瘤患者（年龄从1个月至14岁）。受累部位包括颈部（8例）、纵隔（6例）和腹部（3例）。主要症状包括腹痛、呼吸问题、乳糜胸、胸腔积液和肺炎球菌败血症。除1例仅接受活检的患者外，其余患者均尝试进行了根治性切除。对于无法切除的肿瘤，随后观察其并发症的发生情况。这11例患者的随访时间为2至6年。其中2例已完全消退，5例病情稳定，4例需要再次手术。在病情稳定的5例患者中，均未出现因肿块导致的感染或压迫等并发症。对于无症状患者，似乎残留的淋巴管瘤部分会消退或至少不会进展，无需进一步切除。
