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[类狼疮性利什曼病]

[Lupoid leishmaniasis].

作者信息

Ysmail-Dahlouk M, Amar Khodja A, Ysmail-Dahlouk S, Ait Belkacem F

机构信息

Service de Dermatologie, CHU Mustapha, Algérie.

出版信息

Ann Dermatol Venereol. 1994;121(2):103-6.

PMID:7979013
Abstract

INTRODUCTION

Due to the wide variety of clinical pictures, several terms have been used in the literature reporting cases of lupoid leishmaniasis, including chronic leishmaniasis and recurrent leishmaniasis.

CASES

We report three new cases, two of which presented the classical features, and a third one with an unusual distribution of the lesions.

DISCUSSION

Lupoid leishmaniasis is a particular evolving form of cutaneous leishmaniasis with characteristic spreading of the initial nodule, leading to a plaque simulating discoid lupus. Leishmaniasis major was identified in all three patients and recognized as the zoonotic leishmaniasis which usually presents as a classical oriental sore. A clinical course to lupoid leishmaniasis is probably related to changes in cell-mediated immunity leading to localized or diffuse lesions.

摘要

引言

由于临床表现多种多样,在报道类狼疮型利什曼病病例的文献中使用了多个术语,包括慢性利什曼病和复发性利什曼病。

病例

我们报告3例新病例,其中2例具有典型特征,第3例病变分布异常。

讨论

类狼疮型利什曼病是皮肤利什曼病的一种特殊演变形式,具有初始结节特征性扩散,导致类似盘状狼疮的斑块。所有3例患者均确诊为大型利什曼原虫感染,被认为是通常表现为典型东方疖的人畜共患利什曼病。类狼疮型利什曼病的临床病程可能与细胞介导免疫的变化有关,从而导致局部或弥漫性病变。

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