Department of Dermatology, Combined Military Hospital, Peshawar, Faisal, Pakistan.
Indian J Dermatol Venereol Leprol. 2010 Jan-Feb;76(1):85. doi: 10.4103/0378-6323.58698.
BACKGROUND: Lupoid cutaneous leishmaniasis (CL) is known as the chronic form of CL. However, keeping its clinical presentation in view, there is a need to revisit this form of disease. AIMS: To redefine/describe lupoid CL in view of clinical features. METHODS: It was a case series seen in Muzaffarabad (Pakistan) from Jan 2006 to May 2008. All patients clinically suggestive and consistent with laboratory diagnosis of CL were registered. Patients of all age groups and either sex having cutaneous lesions resembling lupus vulgaris or lupus erythematosus on the face or elsewhere were included in the study. Those having chronic fluctuating/relapsing course or scarring within the lesions were also included. Various demographic features of the patients and clinical patterns were recorded. Descriptive statistics were used for analysis. RESULTS: Of 254 registered patients of CL, 16 (6.3%) were diagnosed as lupoid CL. None of the patients had scarred lesions. Age ranged from 38 to 75 (55 + 15.11) years and duration of lesions varied from 4 to 32 (14.25 + 07.59) weeks. All patients had lesions over the face. Thirteen (81.25%) had a large solitary plaque extending over the nose and a large part of the cheeks and three (18.75%) had multiple lesions. Lesions were central/nasal in two (12.5%), unilateral/asymmetrical in four (25%) and bilateral/symmetrical in 10 (62.5%). Morphological patterns included erythematous/infiltrated (7), psoriasiform (6), ulcerated/crusted (2) and Discoid lupus erythematosus (DLE)[G1] like (1). CONCLUSION: Lupoid CL is not strictly a chronic form of disease, which presents on the face from the very onset and shows no scarring or recurrence.
背景:狼疮样皮肤利什曼病(CL)被认为是 CL 的慢性形式。然而,鉴于其临床表现,有必要重新审视这种疾病形式。
目的:根据临床特征重新定义/描述狼疮样 CL。
方法:这是 2006 年 1 月至 2008 年 5 月在穆扎法拉巴德(巴基斯坦)观察到的一系列病例。所有具有 CL 临床特征和实验室诊断的患者均进行了登记。研究纳入了所有年龄组和性别,具有面部或其他部位类似狼疮样或红斑狼疮样皮肤损害的患者。还包括具有慢性波动/复发过程或病变内瘢痕形成的患者。记录了患者的各种人口统计学特征和临床模式。使用描述性统计进行分析。
结果:在登记的 254 例 CL 患者中,16 例(6.3%)被诊断为狼疮样 CL。没有患者有瘢痕病变。年龄范围为 38 至 75 岁(55 + 15.11 岁),病变持续时间为 4 至 32 周(14.25 + 07.59 周)。所有患者的面部均有病变。13 例(81.25%)有一个大的单一斑块,延伸至鼻子和大部分脸颊,3 例(18.75%)有多发性病变。病变在 2 例(12.5%)中为中央/鼻型,在 4 例(25%)中为单侧/不对称型,在 10 例(62.5%)中为双侧/对称型。形态学模式包括红斑/浸润型(7 例)、银屑病样型(6 例)、溃疡性/结痂型(2 例)和盘状红斑狼疮样(DLE)[G1]型(1 例)。
结论:狼疮样 CL 并非严格的慢性疾病形式,它从一开始就出现在面部,且无瘢痕或复发。
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