Masood Sadia, Naveed Shaheen, Alvi Rehan Uddin
Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Trop Doct. 2012 Apr;42(2):120-1. doi: 10.1258/td.2011.110396. Epub 2012 Feb 15.
Cutaneous leishmaniasis is a protozoan disease caused by Leishmania and transmitted by the bite of some species of sand flies. Usually it presents with variety of clinical manifestations depending on both the infecting species of Leishmania and the immune response of the host. Leishmaniasis recidivans cutis (LRC) is a unique form of cutaneous leishmaniasis characterized by unusual clinical features and its chronic relapsing nature. It is an evolving form of cutaneous leishmaniasis which clinically presents as a spreading of the initial nodule, leading to a plaque formation simulating discoid lupus erythematosus. A clinical course of leishmania recidivans is probably related to changes in cell-mediated immunity leading to localized or diffuse lesions. We report a case that presented with infiltrated, atrophic plaque on a patient's face. Clinically, the lesion resembled the lesion of discoid lupus erythematosus and lupus vulgaris but the cutaneous biopsy proved the diagnosis to be LRC.
皮肤利什曼病是一种由利什曼原虫引起的原生动物疾病,通过某些种类的白蛉叮咬传播。通常,根据感染的利什曼原虫种类和宿主的免疫反应,它会呈现出多种临床表现。皮肤复发性利什曼病(LRC)是皮肤利什曼病的一种独特形式,其特征是具有不寻常的临床特征及其慢性复发性。它是皮肤利什曼病的一种演变形式,临床上表现为初始结节扩散,导致形成类似盘状红斑狼疮的斑块。皮肤复发性利什曼病的临床病程可能与细胞介导免疫的变化有关,从而导致局部或弥漫性病变。我们报告了一例患者面部出现浸润性萎缩性斑块的病例。临床上,该病变类似于盘状红斑狼疮和寻常狼疮的病变,但皮肤活检证实诊断为皮肤复发性利什曼病。